Aortic valve calcification – the role of inflammation and fibrosis

نویسندگان

  • K Pissaridi
  • V Dritsa
  • J Anastassopoulou
  • E Koutoulakis
  • I Mamarelis
  • Chr Kotoulas
چکیده

Background Pathogenesis of aortic valve calcificationis a multifunctional processassociated with various risk factors, while heart valve replacement is the only established treatment. Unfortunately, the real mechanism of the valve calcification remains still unknown. Herewith, we investigate the changes in molecular levelof aortic valve tissues in order to characterize the mineral deposits and understand the mechanism of aortic valve mineralization and stenosis.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2013